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Article

Genetic Sources of Subcomponents of Event-Related Potential in the Dimension of Psychosis Analyzed From the B-SNIP Study.

The American journal of psychiatry - 1 May 2015

Narayanan Balaji, Ethridge Lauren E, O'Neil Kasey, Dunn Sabra, Mathew Ian, Tandon Neeraj, Calhoun Vince D, Ruaño Gualberto, Kocherla Mohan, Windemuth Andreas, Clementz Brett A, Tamminga Carol A, Sweeney John A, Keshavan Matcheri S, Pearlson Godfrey D

Abstract excerpt

OBJECTIVE: Biological risk factors underlying psychosis are poorly understood. Biological underpinnings of the dimension of psychosis can be derived using genetic associations with intermediate phenotypes such as subcomponents of auditory event-related potentials (ERPs). Various ERP subcomponent abnormalities in schizophrenia and psychotic bipolar disorder are heritable and are expressed in unaffected relatives,...

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Identifiers

PMID: 25615564
DOI: 10.1176/appi.ajp.2014.13101411
PMCID: PMC4455958

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