Article
Neurophysiologic effect of GWAS derived schizophrenia and bipolar risk variants.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 1 Jan 2014
Hall Mei-Hua, Levy Deborah L, Salisbury Dean F, Haddad Steve, Gallagher Patience, Lohan Mary, Cohen Bruce, Ongür Dost, Smoller Jordan W
Abstract excerpt
Genome-wide association studies (GWAS) have identified multiple single nucleotide polymorphisms (SNPs) as disease associated variants for schizophrenia (SCZ), bipolar disorder (BPD), or both. Although these results are statistically robust, the functional effects of these variants and their role in the pathophysiology of SCZ or BPD remain unclear. Dissecting the effects of risk genes on distinct domains of brain...
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