Article
Identification of Distinct Psychosis Biotypes Using Brain-Based Biomarkers.
The American journal of psychiatry - 1 Apr 2016
Clementz Brett A, Sweeney John A, Hamm Jordan P, Ivleva Elena I, Ethridge Lauren E, Pearlson Godfrey D, Keshavan Matcheri S, Tamminga Carol A
Abstract excerpt
OBJECTIVE: Clinical phenomenology remains the primary means for classifying psychoses despite considerable evidence that this method incompletely captures biologically meaningful differentiations. Rather than relying on clinical diagnoses as the gold standard, this project drew on neurobiological heterogeneity among psychosis cases to delineate subgroups independent of their phenomenological manifestations....
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