Article
Strategies for Advancing Disease Definition Using Biomarkers and Genetics: The Bipolar and Schizophrenia Network for Intermediate Phenotypes.
Biological psychiatry. Cognitive neuroscience and neuroimaging - 1 Jan 2017
Tamminga Carol A, Pearlson Godfrey D, Stan Ana D, Gibbons Robert D, Padmanabhan Jaya, Keshavan Matcheri, Clementz Brett A
Abstract excerpt
It is critical for psychiatry as a field to develop approaches to define the molecular, cellular, and circuit basis of its brain diseases, especially for serious mental illnesses, and then to use these definitions to generate biologically based disease categories, as well as to explore disease mechanisms and illness etiologies. Our current reliance on phenomenology is inadequate to support exploration of...
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