Article
A review of endophenotypes in schizophrenia and autism: The next phase for understanding genetic etiologies.
American journal of medical genetics. Part C, Seminars in medical genetics - 1 Sept 2017
DiLalla Lisabeth F, McCrary Megan, Diaz Emma
Abstract excerpt
Many psychiatric disorders are caused by multiple genes and multiple environmental factors, making the identification of specific genetic risk factors for these disorders difficult. Endophenotypes are behaviors or characteristics that are intermediate between the genotype and a phenotype of interest. Because they are more directly related to the gene action than is the endpoint disorder, they may be useful in the...
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