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Article

Cis-element architecture of Nrf2-sMaf heterodimer binding sites and its relation to diseases.

Archives of pharmacal research - 1 Mar 2020

Otsuki Akihito, Yamamoto Masayuki

Abstract excerpt

Cellular detoxication is essential for health because it provides protection against various chemicals and xenobiotics. The KEAP1-NRF2 system is important for cellular defense against oxidative and electrophilic stresses as NRF2 activates the transcription of an array of cytoprotective genes, including drug-metabolizing and antioxidant enzymes, in a stress-dependent manner. The CNC family of transcription...

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Share to Enhancer Elements, Genetic
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to NF-E2-Related Factor 2

Share to Polymorphism, Single Nucleotide

Share to Pulmonary Disease, Chronic Obstructive

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Identifiers

PMID: 31792803
DOI: 10.1007/s12272-019-01193-2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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