Article
Genetic Susceptibility to Hepatic Sinusoidal Obstruction Syndrome in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation - 1 May 2020
Ansari Marc, Petrykey Kateryna, Rezgui Mohamed Aziz, Del Vecchio Veronica, Cortyl Jacques, Ralph Reginald-Olivier, Nava Tiago, Beaulieu Patrick, St-Onge Pascal, Jurkovic Mlakar Simona, Huezo-Diaz Curtis Patricia, Uppugunduri Chakradhara Rao S, Lesne Laurence, Théoret Yves, Chalandon Yves, Bartelink Imke H, Boelens Jaap-Jan, Bredius Robbert G M, Dalle Jean-Hugues, Lewis Victor, Kangarloo Bill S, Peters Christina, Sinnett Daniel, Bittencourt Henrique, Krajinovic Maja
Abstract excerpt
Sinusoidal obstruction syndrome (SOS) is a well-recognized and potentially life-threatening complication of hematopoietic stem cell transplantation (HSCT). SOS arises from endothelial cell damage and hepatocellular injury mostly due to the transplantation conditioning regimens but also to other patient, disease, and treatment-related factors. Understanding risk factors associated with the development of SOS is...
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