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Clinically relevant germline variants in allogeneic hematopoietic stem cell transplant recipients

4 Oct 2022

Abstract excerpt

Allogeneic hematopoietic stem cell transplantation (HSCT) provides patients with severe hematologic disease a well-established potential for curation. Incorporation of germline analyses in the workup of HSCT patients is not a common practice. Recognizing rare harmful germline variants may however affect patients' pre-transplantation care, choice of the stem cell donor, and complication risks. We analyzed a...

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PMID: 36195768
DOI: 10.1038/s41409-022-01828-x

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