Article
Genetic variability of five ADRB2 polymorphisms among Mexican Amerindian ethnicities and the Mestizo population.
PloS one - 1 Jan 2019
Salas-Martínez María Guadalupe, Saldaña-Alvarez Yolanda, Cordova Emilio J, Mendiola-Soto Diana Karen, Cid-Soto Miguel A, Luckie-Duque Angélica, Vicenteño-Ayala Hermenegildo, Barajas-Olmos Francisco, Contreras-Cubas Cecilia, García-Ortiz Humberto, Jiménez-Ruíz Juan L, Centeno-Cruz Federico, Martínez-Hernández Angélica, Mendoza-Caamal Elvia C, Mirzaeicheshmeh Elaheh, Orozco Lorena
Abstract excerpt
The Mexican population is characterized by high and particular admixture, and the picture of variants associated with disease remains unclear. Here we investigated the distribution of single nucleotide polymorphisms (SNPs) in the Mexican population. We focused on two non-synonymous and three synonymous SNPs in the beta-2 adrenergic receptor gene (ADRB2), which plays key roles in energy balance regulation. These...
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