Article
Variation at diabetes- and obesity-associated Loci may mirror neutral patterns of human population diversity and diabetes prevalence in India.
Annals of human genetics - 1 Sept 2013
Raj Srilakshmi M, Halebeedu Pradeep, Kadandale Jayarama S, Mirazon Lahr Marta, Gallego Romero Irene, Yadhav Jamuna R, Iliescu Mircea, Rai Niraj, Crivellaro Federica, Chaubey Gyaneshwer, Villems Richard, Thangaraj Kumarasamy, Muniyappa Kalappagowda, Chandra H Sharat, Kivisild Toomas
Abstract excerpt
South Asian populations harbor a high degree of genetic diversity, due in part to demographic history. Two studies on genome-wide variation in Indian populations have shown that most Indian populations show varying degrees of admixture between ancestral north Indian and ancestral south Indian components. As a result of this structure, genetic variation in India appears to follow a geographic cline. Similarly,...
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