Article
EBV-Positive Primary Large B-Cell Lymphoma: The Role of Immunohistochemistry and XPO1 in the Diagnosis of Mediastinal Lymphomas.
Applied immunohistochemistry & molecular morphology : AIMM - 1 Jan 2000
Maracaja Danielle L V, Puthenpura Vidya, Pels Salley G, O'Malley Dennis P, Sklar Jeffrey L, Finberg Karin E, Xu Mina L
Abstract excerpt
Primary mediastinal (thymic) large B-cell lymphoma (PMBL) is described as almost always negative for Epstein-Barr virus (EBV). In the context of a mediastinal lymphoma, the distinction between PMBL, classical Hodgkin lymphoma, diffuse large B-cell lymphoma, and mediastinal gray-zone lymphoma can be very difficult; hence, EBV positivity often argues against PMBL. We present a 19-year-old man with mediastinal mass...
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