Article
Molecular features of primary mediastinal B-cell lymphoma: involvement of p16INK4A, p53 and c-myc.
British journal of haematology - 1 Oct 1999
Scarpa A, Moore P S, Rigaud G, Inghirami G, Montresor M, Menegazzi M, Todeschini G, Menestrina F
Abstract excerpt
Primary mediastinal B-cell lymphoma (PMBL) shows chromosome 9p anomalies in 50% of cases. Based on reports that p16INK4A gene, located on this chromosomal arm, is frequently altered in aggressive lymphomas, we analysed for alterations of this gene in 27 cases of PMBL, which were part of a series of 32 PMBL cases that have been characterized for alterations in c-myc, p53, N-ras, bcl-1, bcl-2, bcl-6 and for...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
