Article
Targeted Mutational Profiling Reveals Clonal Relationships in Metachronous Occurrence of Classic Hodgkin and Mediastinal Large B-Cell Lymphomas.
The American journal of surgical pathology - 1 Jan 2023
Singh Kunwar, Lezama Lhara S, Kurzer Jason, Oak Jean, Schultz Liora M, Walkush Ann, Cheng Tse-Chang, Chen Everett H, May William A, Chang Cheryl, Link Michael P, Advani Ranjana H, Suarez Carlos J, Natkunam Yasodha
Abstract excerpt
Classic Hodgkin lymphoma (CHL) patients may infrequently present with a prior or recurrent disease with discordant histology resembling non-Hodgkin lymphomas. These include primary mediastinal large B-cell lymphoma (PMBL), diffuse large B-cell lymphoma (DLBCL), or mediastinal gray-zone lymphoma (MGZL). Such patients are often refractory to standard therapy and their diagnosis is hampered by significant...
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