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Article

STAT6 is a cargo of exportin 1: Biological relevance in primary mediastinal B-cell lymphoma.

Cellular signalling - 1 Jun 2018

Miloudi Hadjer, Leroy Karen, Jardin Fabrice, Sola Brigitte

Abstract excerpt

Primary mediastinal B-cell lymphoma (PMBL) is a distinct B-cell lymphoma subtype with unique clinicopathological and molecular features. PMBL cells are characterised by several genetic abnormalities that conduct to the constitutive activation of the Janus kinase 2/signal transducer and activator of transcription 6 (JAK2/STAT6) signalling pathway. Among recurrent genetic changes in PMBL, we previously reported...

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Topics

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Share to Active Transport, Cell Nucleus
Share to Exportin 1 Protein
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Lymphoma, Large B-Cell, Diffuse

Share to Mediastinal Neoplasms

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Source

Identifiers

PMID: 29501729
DOI: 10.1016/j.cellsig.2018.02.016

Genes

STAT6
XPO1
JAK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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