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Article

Identification of Primary Mediastinal Large B-cell Lymphoma at Nonmediastinal Sites by Gene Expression Profiling.

The American journal of surgical pathology - 1 Oct 2015

Yuan Ji, Wright George, Rosenwald Andreas, Steidl Christian, Gascoyne Randy D, Connors Joseph M, Mottok Anja, Weisenburger Dennis D, Greiner Timothy C, Fu Kai, Smith Lynette, Rimsza Lisa M, Jaffe Elaine S, Campo Elias, Martinez Antonio, Delabie Jan, Braziel Rita M, Cook James R, Ott German, Vose Julie M, Staudt Louis M, Chan Wing C

Abstract excerpt

Mediastinal involvement is considered essential for the diagnosis of primary mediastinal large B-cell lymphoma (PMBL). However, we have observed cases of diffuse large B-cell lymphoma (DLBCL) with features of PMBL but without detectable mediastinal involvement. The goal was to assess our previously established gene expression profiling (GEP) signature for PMBL in classifying these cases. In a large series of...

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Share to B7-H1 Antigen
Share to Chromosomes, Human, Pair 9

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Disease-Free Survival

Share to Gene Rearrangement

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Share to Lymphoma, Large B-Cell, Diffuse

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Source

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Identifiers

PMID: 26135560
DOI: 10.1097/PAS.0000000000000473
PMCID: PMC7742851

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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