Genome-wide association study reveals two novel risk alleles for incident obstructive sleep apnea in the EPISONO cohort.

doi:10.1016/j.sleep.2019.08.003

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Article

Genome-wide association study reveals two novel risk alleles for incident obstructive sleep apnea in the EPISONO cohort.

Sleep medicine - 1 Feb 2020

Farias Tempaku Priscila, Leite Santoro Marcos, Bittencourt Lia, D'Almeida Vania, Iole Belangero Sintia, Tufik Sergio

Abstract excerpt

OBJECTIVE/BACKGROUND: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder that has a complex phenotype. Currently, few genes have been linked with OSA. Thus, the aim of this study was to conduct a genome-wide association study (GWAS) of the apnea-hypopnea index (AHI) variation alo...

Topics

Adult
Alleles
Brazil
Female
Genome-Wide Association Study
Humans
Incidence
Longitudinal Studies
Male
Middle Aged
Polysomnography
Prospective Studies
Proteins
Sialyltransferases
Sleep Apnea, Obstructive
Time Factors

Source

Open in PubMed

Identifiers

PMID: 31786426
DOI: 10.1016/j.sleep.2019.08.003

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-31786426-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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