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Discovery of genomic loci associated with sleep apnea risk through multi-trait GWAS analysis with snoring.

Sleep - 9 Mar 2023

Campos Adrian I, Ingold Nathan, Huang Yunru, Mitchell Brittany L, Kho Pik-Fang, Han Xikun, García-Marín Luis M, Ong Jue-Sheng, Law Matthew H, Yokoyama Jennifer S, Martin Nicholas G, Dong Xianjun, Cuellar-Partida Gabriel, MacGregor Stuart, Aslibekyan Stella, Rentería Miguel E

Abstract excerpt

STUDY OBJECTIVES: Despite its association with severe health conditions, the etiology of sleep apnea (SA) remains understudied. This study sought to identify genetic variants robustly associated with SA risk. METHODS: We performed a genome-wide association study (GWAS) meta-analysis of SA across five cohorts (NTotal = 523 366), followed by a multi-trait analysis of GWAS (multi-trait analysis of genome-wide...

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Identifiers

PMID: 36525587
DOI: 10.1093/sleep/zsac308
PMCID: PMC9995783

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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