Article

Characterization of Genetic and Phenotypic Heterogeneity of Obstructive Sleep Apnea Using Electronic Health Records

2019-08-05

Abstract excerpt

<h4>ABSTRACT</h4> Obstructive sleep apnea (OSA) is defined by frequent episodes of reduced or complete cessation of airflow during sleep and is linked to negative health outcomes. Understanding the genetic factors influencing expression of OSA may lead to new treatment strategies. Electronic health records can be leveraged to both validate previously reported OSA-associated genomic variation and detect novel rela...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 578f1acd-1dd9-5429-8db7-3972099924b9
DOI: 10.1101/724443

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Characterization of Genetic and Phenotypic Heterogeneity of Obstructive Sleep Apnea Using Electronic Health RecordsDOI 10.1101/724443Read

Characterization of genetic and phenotypic heterogeneity of obstructive sleep apnea using electronic health records.Semantic proximity Read

Associations between obstructive sleep apnea and comorbidities in a large clinical biobankSemantic proximity Read

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic healthSemantic proximity Read

Genetic analysis of obstructive sleep apnoea discovers a strong association with cardiometabolic healthSemantic proximity Read

Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea SubtypeSemantic proximity Read

Gene-Excessive Sleepiness Interactions Suggest Treatment Targets for Obstructive Sleep Apnea SubtypeSemantic proximity Read

COMPREHENSIVE GENETIC INVESTIGATION REVEALS HETEROGENEOUS PATHWAYS TO OBSTRUCTIVE SLEEP APNEASemantic proximity Read

The genetics of obstructive sleep apnoea.Semantic proximity Read

From Normal Variation in Sleep to Clinical Sleep Disorders: Genetic Insights from Over One Million IndividualsSemantic proximity Read

Phenotypes in obstructive sleep apnea: A definition, examples and evolution of approaches.Semantic proximity Read

Disparities and genetic risk factors in obstructive sleep apnea.Semantic proximity Read

Genomic approaches to understanding obstructive sleep apnea.Semantic proximity Read