Article
Discrimination of low- and high-grade appendiceal mucinous neoplasms by targeted sequencing of cancer-related variants.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Jul 2019
LaFramboise William A, Pai Reetesh K, Petrosko Patti, Belsky Michael A, Dhir Apoorv, Howard Peter G, Becich Michael J, Holtzman Matthew P, Ahrendt Steven A, Pingpank James F, Zeh Herbert J, Dhir Rajiv, Bartlett David L, Choudry Haroon A
Abstract excerpt
DNA was obtained from matching micro-dissected, primary tumor cells, paired metastases, and peripheral blood mononuclear cells (germline) from patients with appendiceal mucinous neoplasms. We compared specimens from patient cohorts comprising low-grade adenomucinous neoplasm versus high-grade mucinous adenocarcinoma using a targeted, amplicon sequencing panel of 409 cancer related genes (Ion Torrent Comprehensive...
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