Article
ITGAM is associated with disease susceptibility and renal nephritis of systemic lupus erythematosus in Hong Kong Chinese and Thai.
Human molecular genetics - 1 Jun 2009
Yang Wanling, Zhao Minghui, Hirankarn Nattiya, Lau Chak Sing, Mok Chi Chiu, Chan Tak Mao, Wong Raymond W S, Lee Ka Wing, Mok Mo Yin, Wong Sik Nin, Avihingsanon Yingyos, Lin Irene Oi, Lee Tsz Leung, Ho Marco Hok Kung, Lee Pamela Pui Wah, Wong Wilfred Hing Sang, Sham Pak Chung, Lau Yu Lung
Abstract excerpt
ITGAM was recently found to be associated with systemic lupus erythematosus (SLE) in populations of not only European ancestry, but also in Hispanic- and African-Americans, Mexicans and Colombians. The risk alleles in the gene, however, were found to be monomorphic in two Asian populations examined: Japanese and Korean. In this study, using a collection of 910 SLE patients and 2360 controls from Chinese living in...
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