scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development.

doi:10.1101/gad.9.19.2384

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Article

scratch, a pan-neural gene encoding a zinc finger protein related to snail, promotes neuronal development.

Genes & development - 1 Oct 1995

Roark M, Sturtevant M A, Emery J, Vaessin H, Grell E, Bier E

Abstract excerpt

The Drosophila scratch (scrt) gene is expressed in most or all neuronal precursor cells and encodes a predicted zinc finger transcription factor closely related to the product of the mesoderm determination gene snail (sna). Adult flies homozygous for scrt null alleles have a reduced number of photoreceptors in the eye, and embryos lacking the function of both scrt and the pan-neural gene deadpan (dpn), which...

Topics

Amino Acid Sequence
Animals
Cell Differentiation
Chromosome Mapping
DNA-Binding Proteins
Drosophila
Drosophila Proteins
Gene Expression Regulation, Developmental
In Situ Hybridization
Mesoderm
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Neurons

Phenotype

Photoreceptor Cells, Invertebrate

Sequence Analysis

Sequence Homology, Amino Acid

Snail Family Transcription Factors

Source

Open in PubMed

Identifiers

PMID: 7557390
DOI: 10.1101/gad.9.19.2384

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7557390-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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