Article
CYP2C19 genetic polymorphism in the Vietnamese population.
Annals of human biology - 1 Sept 2019
Vu Nhung Phuong, Nguyen Hoa Thi Thanh, Tran Ngoc Thi Bich, Nguyen Ton Dang, Huynh Hue Thi Thu, Nguyen Xuan Thi, Nguyen Duong Thuy, Nong Hai Van, Nguyen Ha Hai
Abstract excerpt
Background: Genetic polymorphism of CYP2C19 has been shown to affect enzyme activity and thereby contribute to inter-individual variability in drug metabolism and response. The complete genetic variation of CYP2C19 in Vietnam still remains obscure even though data of common alleles in Vietnamese Kinh have been reported.Aim: To establish the extent of CYP2C19 polymorphism in Vietnamese.Subjects and methods: The...
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