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Article

ADDO: a comprehensive toolkit to detect, classify and visualize additive and non-additive quantitative trait loci.

Bioinformatics (Oxford, England) - 1 Mar 2020

Cui Leilei, Yang Bin, Pontikos Nikolas, Mott Richard, Huang Lusheng

Abstract excerpt

MOTIVATION: During the past decade, genome-wide association studies (GWAS) have been used to map quantitative trait loci (QTLs) underlying complex traits. However, most GWAS focus on additive genetic effects while ignoring non-additive effects, on the assumption that most QTL act additively. Consequently, QTLs driven by dominance and other non-additive effects could be overlooked. RESULTS: We developed ADDO, a...

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PMID: 31764991
DOI: 10.1093/bioinformatics/btz786

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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