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Article

EPIQ-efficient detection of SNP-SNP epistatic interactions for quantitative traits.

Bioinformatics (Oxford, England) - 15 Jun 2014

Arkin Ya'ara, Rahmani Elior, Kleber Marcus E, Laaksonen Reijo, März Winfried, Halperin Eran

Abstract excerpt

MOTIVATION: Gene-gene interactions are of potential biological and medical interest, as they can shed light on both the inheritance mechanism of a trait and on the underlying biological mechanisms. Evidence of epistatic interactions has been reported in both humans and other organisms. Unlike single-locus genome-wide association studies (GWAS), which proved efficient in detecting numerous genetic loci related...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24931983
DOI: 10.1093/bioinformatics/btu261
PMCID: PMC4229902

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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