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Article

High glucose concentrations mask cellular phenotypes in a stem cell model of tuberous sclerosis complex.

Epilepsy & behavior : E&B - 1 Dec 2019

Rocktäschel Paula, Sen Arjune, Cader M Zameel

Abstract excerpt

Tuberous sclerosis complex (TSC) is a neurodevelopmental disorder caused by deletions in the TSC1 or TSC2 genes that is associated with epilepsy in up to 90% of patients. Seizures are suggested to start in benign brain tumors, cortical tubers, or in the perituberal tissue making these tubers an interesting target for further research into mechanisms underlying epileptogenesis in TSC. Animal models of TSC...

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Source

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Identifiers

PMID: 31761686
DOI: 10.1016/j.yebeh.2019.106581
PMCID: PMC6943812

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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