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Article

DNA damage responses in murine Pre-B cells with genetic deficiencies in damage response genes.

Cell cycle (Georgetown, Tex.) - 1 Jan 2020

Innes Cynthia L, Hesse Jill E, Morales Abigail J, Helmink Beth A, Schurman Shepherd H, Sleckman Barry P, Paules Richard S

Abstract excerpt

DNA damage can be generated in multiple ways from genotoxic and physiologic sources. Genotoxic damage is known to disrupt cellular functions and is lethal if not repaired properly. We compare the transcriptional programs activated in response to genotoxic DNA damage induced by ionizing radiation (IR) in abl pre-B cells from mice deficient in DNA damage response (DDR) genes Atm, Mre11, Mdc1, H2ax, 53bp1, and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 31757180
DOI: 10.1080/15384101.2019.1693118
PMCID: PMC6927727

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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