Function and Molecular Mechanism of the DNA Damage Response in Immunity and Cancer Immunotherapy.

Abstract excerpt

The DNA damage response (DDR) is an organized network of multiple interwoven components evolved to repair damaged DNA and maintain genome fidelity. Conceptually the DDR includes damage sensors, transducer kinases, and effectors to maintain genomic stability and accurate transmission of genetic information. We have recently gained a substantially improved molecular and mechanistic understanding of how DDR...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Adaptive Immunity
• Share to Disease Management
• Share to Disease Susceptibility