Article
Differential DNA Damage Response of Peripheral Blood Lymphocyte Populations.
Frontiers in immunology - 1 Jan 2021
Felgentreff Kerstin, Schuetz Catharina, Baumann Ulrich, Klemann Christian, Viemann Dorothee, Ursu Simona, Jacobsen Eva-Maria, Debatin Klaus-Michael, Schulz Ansgar, Hoenig Manfred, Schwarz Klaus
Abstract excerpt
DNA damage occurs constantly in every cell triggered by endogenous processes of replication and metabolism, and external influences such as ionizing radiation and intercalating chemicals. Large sets of proteins are involved in sensing, stabilizing and repairing this damage including control of cell cycle and proliferation. Some of these factors are phosphorylated upon activation and can be used as biomarkers of...
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