Article
Toll-like receptor 4 polymorphisms were associated with low serum pro-inflammatory cytokines in BCG osteitis survivors.
Acta paediatrica (Oslo, Norway : 1992) - 1 Jul 2020
Korppi Matti, Teräsjärvi Johanna, Lauhkonen Eero, Huhtala Heini, Nuolivirta Kirsi, He Qiushui
Abstract excerpt
AIM: The aim of the study was to evaluate the association of Toll-like receptor 4 (TLR4) gene variations with osteitis risk after Bacillus Calmette-Guérin (BCG) vaccination given at birth and with serum cytokine levels measured in adulthood. METHODS: We determined the TLR4 rs4986790 single-nucleotide polymorphism (SNP) in 132 study subjects with BCG osteitis in infancy and compared the genotype distributions and...
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