Article
Toll-like receptor 10 rs10004195 variation may be protective against Bacillus Calmette-Guérin osteitis after newborn vaccination.
Acta paediatrica (Oslo, Norway : 1992) - 1 May 2021
Korppi Matti, Teräsjärvi Johanna, Lauhkonen Eero, Huhtala Heini, Nuolivirta Kirsi, He Qiushui
Abstract excerpt
AIM: Toll-like receptor 1 (TLR1), TLR2, TLR6 and TLR10 form the TLR2 subfamily. In our previous controlled studies in 132 subjects with osteitis after newborn Bacillus Calmette-Guérin (BCG) vaccination, TLR1, TLR2 and TLR6 variations were associated with the risk of BCG osteitis. Now, we evaluated the role of ten single nucleotide polymorphisms (SNP) of the TLR10 gene in this cohort. METHODS: Five synonymous...
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