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Article

Toll-like receptor 2 subfamily gene polymorphisms are associated with Bacillus Calmette-Guérin osteitis following newborn vaccination.

Acta paediatrica (Oslo, Norway : 1992) - 1 May 2015

Pöyhönen Laura, Nuolivirta Kirsi, Vuononvirta Juho, Kröger Liisa, Huhtala Heini, Mertsola Jussi, He Qiushui, Korppi Matti

Abstract excerpt

AIM: Toll-like receptor (TLR) 1, 2, 6 and 10, the TLR2 subfamily, are known to be associated with immunity against tuberculosis. We evaluated whether polymorphisms in genes encoding TLR1, TLR2 and TLR6 were associated with osteitis in infants who received the Bacillus Calmette-Guérin (BCG) vaccination soon after birth. METHODS: Blood samples from 132 adults aged 21-49 who had BCG osteitis in early childhood were...

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Source

Identifiers

PMID: 25605403
DOI: 10.1111/apa.12927

Genes

TLR2
TLR1
TLR6

Variants

rs5743618
rs5743618
rs5743618

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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