Article
Pancreatic Islet Transcriptional Enhancers and Diabetes.
Current diabetes reports - 21 Nov 2019
Cebola Inês
Abstract excerpt
PURPOSE OF REVIEW: Common genetic variants that associate with type 2 diabetes risk are markedly enriched in pancreatic islet transcriptional enhancers. This review discusses current advances in the annotation of islet enhancer variants and their target genes. RECENT FINDINGS: Recent methodological advances now allow genetic and functional mapping of diabetes causal variants at unprecedented resolution. Mapping...
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