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Article

Transcriptional Regulation of the Pancreatic Islet: Implications for Islet Function.

Current diabetes reports - 1 Sept 2015

Stitzel Michael L, Kycia Ina, Kursawe Romy, Ucar Duygu

Abstract excerpt

Islets of Langerhans contain multiple hormone-producing endocrine cells controlling glucose homeostasis. Transcription establishes and maintains islet cellular fates and identities. Genetic and environmental disruption of islet transcription triggers cellular dysfunction and disease. Early transcriptional regulation studies of specific islet genes, including insulin (INS) and the transcription factor PDX1,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26272056
DOI: 10.1007/s11892-015-0635-0
PMCID: PMC4593392

Genes

INS
PDX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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