Article
TZAP Mutation Leads to Poor Prognosis of Patients with Breast Cancer †.
Medicina (Kaunas, Lithuania) - 18 Nov 2019
Heo Yu-Ran, Lee Moo-Hyun, Kwon Sun-Young, Cho Jihyoung, Lee Jae-Ho
Abstract excerpt
Background and Objectives: ZBTB48 is a telomere-associated factor that has been renamed as telomeric zinc finger-associated protein (TZAP). It binds preferentially to long telomeres, competing with telomeric repeat factors 1 and 2. Materials and Methods: We analyzed the TZAP mutation in 128 breast carcinomas (BCs). In addition, its association with telomere length was investigated. Results: The TZAP mutation...
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