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A Genetic Variant of the BTLA Gene is Related to Increased Risk and Clinical Manifestations of Breast Cancer in Chinese Women.

Clinical breast cancer - 1 Oct 2021

Zhao Rui-Peng, Li Zhi, Li Chang, Xu Kang, Zhen Lin-Lin, Song Wei, Shi Jian-Hua

Abstract excerpt

BACKGROUND: B and T lymphocyte attenuator (BTLA), an immunoinhibitory receptor, is shown to suppress the lymphocyte activation. Several studies addressed the relationship between the BTLA rs1982809 polymorphism and the risk of cancer. PATIENTS AND METHODS: To identify the effects of this polymorphism on the risk of breast cancer (BC), this study examined Chinese women from China, Jiangsu Province. This study...

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PMID: 33642196
DOI: 10.1016/j.clbc.2020.12.009

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