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Zinc Transporters and the Progression of Breast Cancers

30 Sept 2018

Abstract excerpt

Zinc (Zn) is an essential heavy metal utilized in numerous biological processes in mammals, including its recently described role as a signaling mediator. The movement of Zn in and out of cells, across membranes, is regulated by two protein families: the zinc-regulated transporter (ZRT), iron-regulated transporter (IRT)-like protein (ZIP) and the Zn transporter (ZnT) families. ZIPs and ZnTs maintain intracellular...

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PMID: 30270320
DOI: 10.1248/bpb.b18-00086

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