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Article

Validation of a priori candidate Alzheimer's disease SNPs with brain amyloid-beta deposition.

Scientific reports - 19 Nov 2019

Vacher Michael, Porter Tenielle, Villemagne Victor L, Milicic Lidija, Peretti Madeline, Fowler Christopher, Martins Ralph, Rainey-Smith Stephanie, Ames David, Masters Colin L, Rowe Christopher C, Doecke James D, Laws Simon M

Abstract excerpt

The accumulation of brain amyloid β (Aβ) is one of the main pathological hallmarks of Alzheimer's disease (AD). However, the role of brain amyloid deposition in the development of AD and the genetic variants associated with this process remain unclear. In this study, we sought to identify associations between Aβ deposition and an a priori evidence based set of 1610 genetic markers, genotyped from 505 unrelated...

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PMID: 31745181
DOI: 10.1038/s41598-019-53604-5
PMCID: PMC6863876

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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