Article
Combined Genome-Wide CSF Aβ-42's Associations and Simple Network Properties Highlight New Risk Factors for Alzheimer's Disease.
Journal of molecular neuroscience : MN - 1 Jan 2016
Souza M B R, Araújo G S, Costa I G, Oliveira J R M
Abstract excerpt
The abnormal deposition of amyloid-β protein in the brain plays an important role in Alzheimer's disease (AD), being considered a potential clinical biomarker. To investigate genetic associations with amyloid-β we used biomarker data and genome-wide variants from individuals with AD and mild cognitive impairment in the Alzheimer's Disease Neuroimaging Initiative (ADNI) database. We used a standard linear model...
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