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Article

ABCA7 Genotypes Confer Alzheimer's Disease Risk by Modulating Amyloid-β Pathology.

Journal of Alzheimer's disease : JAD - 21 Mar 2016

Zhao Qing-Fei, Wan Yu, Wang Hui-Fu, Sun Fu-Rong, Hao Xiao-Ke, Tan Meng-Shan, Tan Chen-Chen, Zhang Dao-Qiang, Tan Lan, Yu Jin-Tai

Abstract excerpt

ABCA7 gene has been identified as a strong genetic locus for Alzheimer's disease (AD) susceptibility in genome wide association studies (GWAS). However, the possible roles of ABCA7 variants in AD pathology were not specifically assessed. Using tagger methods, we extracted 15 targeted ABCA7 loci to investigate their associations with cerebrospinal fluid (CSF) and neuroimaging markers in Alzheimer's Disease...

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Source

Identifiers

PMID: 27003212
DOI: 10.3233/JAD-151005

Genes

ABCA7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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