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Polymorphisms in proinflammatory cytokine genes, effect on gene expression and association with preterm delivery in Saudi females.

Cellular and molecular biology (Noisy-le-Grand, France) - 30 Jul 2018

As Sayaril Nada, Bhat Ramesa Shafi, Warsy Arjumand S, Babay Zeneb A, Addar Mohammad H, Shaik Jilani, Al-Marry Bashaier, Al-Daihan Sooad

Abstract excerpt

Genetic polymorphism in proinflammatory cytokine genes may be associated with the etiology of preterm birth (PTB). The current study was designed with the aim to explore the association of genetic polymorphisms and mRNA expression of IL-1α, IL-1β, and TNF-α gene with preterm birth in the Saudi population. Genotyping of genomic DNA of 50 PTB patients and an equal number of controls were carried out using TaqMan...

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PMID: 30084795

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