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Article

A TIR domain receptor-associated protein (TIRAP) variant SNP (rs8177374) confers protection against premature birth.

Journal of perinatology : official journal of the California Perinatal Association - 1 May 2013

Karody V R, Le M, Nelson S, Meskin K, Klemm S, Simpson P, Hines R, Sampath V

Abstract excerpt

OBJECTIVE: To investigate whether single nucleotide polymorphisms (SNPs) in genes encoding the Toll-like receptor (TLR) signaling pathway modulate susceptibility to preterm birth (PTB). STUDY DESIGN: Prospective case-control study examining the contribution of nine TLR SNPs to PTB (<37 weeks) and PTB <32 weeks. Genotyping was done on neonatal blood using a multiplexed single-base extension assay. Chi-square test,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23047423
DOI: 10.1038/jp.2012.120

Genes

TIRAP
IRAK1
TLR2
TLR4
TLR5
TLR9

Provenance

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