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Article

Are Immune Modulating Single Nucleotide Polymorphisms Associated with Necrotizing Enterocolitis?

Scientific reports - 16 Dec 2015

Franklin Ashanti L, Said Mariam, Cappiello Clint D, Gordish-Dressman Heather, Tatari-Calderone Zohreh, Vukmanovic Stanislav, Rais-Bahrami Khodayar, Luban Naomi L C, Devaney Joseph M, Sandler Anthony D

Abstract excerpt

Necrotizing enterocolitis (NEC) is a devastating gastrointestinal emergency. The purpose of this study is to determine if functional single nucleotide polymorphisms (SNPs) in immune-modulating genes pre-dispose infants to NEC. After Institutional Review Board approval and parental consent, buccal swabs were collected for DNA extraction. TaqMan allelic discrimination assays and BglII endonuclease digestion were...

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PMID: 26670709
DOI: 10.1038/srep18369
PMCID: PMC4680983

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TRIM21

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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