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Article

Multigene germline testing for epithelial ovarian cancer in China.

Cancer - 1 May 2026

Li Lei, Song Nan, Zhang Depu, Li Yi, Rao Yang, Liu Chunyan, Qiao Zhiwei, Zhang Jianwei, Shao Kang, Wu Ming

Abstract excerpt

BACKGROUND: Large-scale studies of germline variants in hereditary cancer susceptibility genes among Chinese epithelial ovarian cancer (EOC) patients remain limited. This study assessed the prevalence and clinical significance of germline variants in 21 genes relevant to hereditary breast and ovarian cancer. METHODS: In this multicenter prospective cohort (February 2017-December 2018), 961 unselected EOC patients...

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Source

Identifiers

PMID: 42036915
DOI: 10.1002/cncr.70395

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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