Article
Estimated number of adult survivors of childhood cancer in United States with cancer-predisposing germline variants.
Pediatric blood & cancer - 1 Feb 2020
Wilson Carmen L, Wang Zhaoming, Liu Qi, Ehrhardt Matthew J, Mostafavi Roya, Easton John, Mulder Heather, Hedges Dale J, Wang Shuoguo, Rusch Michael, Edmonson Michael, Levy Shawn, Lanctot Jennifer Q, Currie Kelsey, Lear Matthew, Patel Aman, Sapkota Yadav, Brooke Russell J, Moon Wonjong, Chang Ti-Cheng, Chen Wenan, Kesserwan Chimene A, Wu Gang, Nichols Kim E, Hudson Melissa M, Zhang Jinghui, Robison Leslie L, Yasui Yutaka
Abstract excerpt
PURPOSE: To estimate the absolute number of adult survivors of childhood cancer in the U.S. population who carry a pathogenic or likely pathogenic variant in a cancer predisposition gene. METHODS: Using the Surveillance, Epidemiology, and End Results (SEER) Program, we estimated the number of childhood cancer survivors on December 31, 2016 for each childhood cancer diagnosis, multiplied this by the proportion of...
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