Article

TFEB controls syncytiotrophoblast differentiation

2024-02-21

Abstract excerpt

During human development, a subset of differentiating fetal cells form a temporary organ, the placenta, which invades the uterine wall to support nutrient, oxygen, and waste exchange between the mother and fetus until birth. Most of the human placenta is formed by a syncytial villous structure which arises via cell-cell fusion of underlying fetal trophoblast stem cells. Genetic and functional studies have characte...

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Literature Corpus work: 9e9157f1-b4eb-5ada-ac30-5facf2832814
DOI: 10.1101/2024.02.20.581304

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