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Article

Perampanel attenuates epileptiform phenotype in C6 glioma.

Neuroscience letters - 10 Jan 2020

Mayer Johannes, Kirschstein Timo, Resch Tobias, Porath Katrin, Krause Bernd Joachim, Köhling Rüdiger, Lange Falko

Abstract excerpt

Epileptic seizures are frequent in patients with glioma, and anticonvulsive treatment is often indicated. Glioma cells release glutamate via the Xc- antiporter system, which appears to be a major pathomechanism of glioma-associated seizures and excitotoxicity. In addition, the proliferation and survival of the tumor cells are promoted. Therefore, anticonvulsants that attenuate glutamate-mediated receptor...

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Identifiers

PMID: 31734290
DOI: 10.1016/j.neulet.2019.134629

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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