Article

Transcriptomic Alterations Related to Epilepsy and Tumor Suppression in the Peritumoral Area of a Rat Glioma Model

2021-11-30

Abstract excerpt

Patients with glioma often demonstrate epilepsy. We previously found burst discharges in the peritumoral area in patents with malignant brain tumors during biopsy. Therefore, we hypothesized that the peritumoral area may possess an epileptic focus and that biological alterations in the peritumoral area may cause epileptic symptoms in patients with glioma. To test our hypothesis, we developed a rat model of glioma...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 42c1d668-f9be-514c-a3d9-b8d24ad50fb3
DOI: 10.21203/rs.3.rs-1047051/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Transcriptomic Alterations Related to Epilepsy and Tumor Suppression in the Peritumoral Area of a Rat Glioma ModelDOI 10.21203/rs.3.rs-1047051/v1Read

Glioma-induced alterations in neuronal activity and neurovascular coupling during disease progressionSemantic proximity Read

The complex molecular epileptogenesis landscape of glioblastomaSemantic proximity Read

Integrative analysis of expression profile indicates the ECM receptor and LTP dysfunction in the glioma-related epilepsySemantic proximity Read

Multi‐omics technologies and molecular biomarkers in brain tumor‐related epilepsySemantic proximity Read

A systems level, functional genomics analysis of chronic epilepsy.Semantic proximity Read

Glioblastoma cells imitate neuronal excitability in humansSemantic proximity Read

Correlation of Brain Tumor-related Epilepsy With Clinicopathological Factors in GliomasSemantic proximity Read

Genetic association between epilepsy and gliomas: Insights from Mendelian randomization and single-cell transcriptomic analyses.Semantic proximity Read

Postoperative risk of IDH-mutant glioma-associated seizures and their potential management with IDH-mutant inhibitors.Semantic proximity Read

Differential Expression Analysis of miRNAs and mRNAs in Epilepsy Uncovers Potential BiomarkersSemantic proximity Read

Mapping seizure foci and tumor genetic factors in glioma associated seizure patients.Semantic proximity Read

Tumor-Related Epilepsy and Post-Surgical Outcomes: Tertiary Hospital Experience in VietnamSemantic proximity Read