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Article

Involvement of P2X7 Receptor in Proliferation and Migration of Human Glioma Cells

1 Jan 2018

Abstract excerpt

Previous studies have demonstrated that activation of P2X7 receptors (P2X7R) results in the proliferation and migration of some types of tumor. Here, we asked whether and how the activated P2X7R contribute to proliferation and migration of human glioma cells. Results showed that the number of P2X7R positive cells was increasing with grade of tumor. In U87 and U251 human glioma cell lines, both expressed P2X7R and...

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PMID: 29546069
DOI: 10.1155/2018/8591397

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