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Article

Exome-chip association analysis of intracranial aneurysms.

Neurology - 4 Feb 2020

van 't Hof Femke N G, Lai Dongbing, van Setten Jessica, Bots Michiel L, Vaartjes Ilonca, Broderick Joseph, Woo Daniel, Foroud Tatiana, Rinkel Gabriel J E, de Bakker Paul I W, Ruigrok Ynte M

Abstract excerpt

OBJECTIVE: To investigate to what extent low-frequency genetic variants (with minor allele frequencies <5%) affect the risk of intracranial aneurysms (IAs). METHODS: One thousand fifty-six patients with IA and 2,097 population-based controls from the Netherlands were genotyped with the Illumina HumanExome BeadChip. After quality control (QC) of samples and single nucleotide variants (SNVs), we conducted a single...

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Identifiers

PMID: 31732565
DOI: 10.1212/WNL.0000000000008665
PMCID: PMC7080288

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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