Article
Evidence in favor of the contribution of genes involved in the maintenance of the extracellular matrix of the arterial wall to the development of intracranial aneurysms.
Human molecular genetics - 15 Nov 2006
Ruigrok Ynte M, Rinkel Gabriël J E, van't Slot Ruben, Wolfs Marcel, Tang Song, Wijmenga Cisca
Abstract excerpt
Intracranial aneurysm is probably a complex disease with both genetic and non-genetic or environmental risk factors contributing to the etiology of the disease. A disruption of the extracellular matrix (ECM) of the arterial wall is a likely factor in the pathogenesis of intracranial aneurysms. We...
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